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With aging, mitochondrial function in senescent cells undergoes complex changes due to intertwined mechanisms, including structural damage (such as swelling, loss of cristae definition and inner membrane disruption), accumulation of mitochondrial DNA (mtDNA) deletions and mutations, and electron transport chain (ETC) impairment (73,74)
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3.2.4.3 Macrophage Macrophages are directly involved in the process of ferroptosis by regulating iron homeostasis
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